Human autoantigen database

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Web1 Jul 2024 · For this study, we used the AAgAtlas 1.0, a database [7] of 1126 autoantigens. From this compilation, we selected 1050 autoantigens based on their predicted propensity to undergo phase separation (see Results and [10]). ... AAgAtlas 1.0: a human autoantigen database. Nucleic Acids Res. (2024) J.A. Toretsky et al. Assemblages: functional units ... WebExplore the Sengenics protein database and access the complete list of Sengenics proteins found on our best-in-class arrays. Services. ... ORVAR Autoantigen Discovery Platform; The Value of Autoantibodies; Bioinformatics for Autoantibodies; Resources. ... HUMAN Double-strand-break repair protein rad21 homolog: hHR21, KIAA0078, SCC1 ...

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Web9 Feb 2000 · The autoantigens were shown to cluster in two discrete cell surface 'membrane blebs'. The larger blebs (called apoptotic bodies) contained predominantly Ro, La, snRNPs, and nucleosomal DNA. The smaller structures were recognized by autoantibodies specific for endoplasmic reticulum components, as well as Ro and ribosomal components [ 12 ]. Web27 Jan 2024 · Autoantibodies are produced to target an individual's own antigens (e.g. proteins). They can trigger autoimmune responses and inflammation, and thus, cause … romantic hindi serials in hotstar

AAgAtlas 1.0: A Database of Human Autoantigens Extracted from ...

WebTo address this need, previously we developed a human autoantigen database, AAgAtlas 1.0, by text-mining and manual curation, which collects 1126 autoantigens associated with 1071 human diseases. AAgAtlas 1.0 provides a user-friendly interface to conveniently browse, retrieve, and download human autoantigen genes, their functional annotation, … WebThe database is freely accessible at http://biokb.ncpsb.org/aagatlas/. We believe this database will be a valuable resource to track and understand human autoantigens as … WebOf these, 23 have previously been identified as autoantigens according to the human autoantigen database AagAtlas . Gene ontology (GO) annotation analysis of the identified proteins’ molecular functions categorized several of them as involved in either the binding or catalytic activity ( Figure 2 B,C). romantic hindi serials 2011

Construction of AAgAtlas 1.0 database. (A) The workflow of …

AAgAtlas 1.0: A human autoantigen database - Arizona …

WebAAgAtlas 1.0: a human autoantigen database Overview of attention for article published in Nucleic Acids Research, October 2016 Summary Blogs Twitter Dimensions citations You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more . Web19 Oct 2016 · The database provides a user-friendly interface to conveniently browse, retrieve and download human autoantigens as well as their associated diseases. The … romantic hindi serials 2020Web1 May 2024 · Although autoimmunity and autoimmune disease (AID) are relatively common, the repertoire of autoantigens is paradoxically very limited. Highly enriched in this autoantigen repertoire are nucleic acids and their binding proteins, which together form large macromolecular structures. romantic hindi song mashup 2022

"Web1 Nov 2024 · In this study, we advanced into determine molecular mimicry between Leishmania sp. and human antigens to related infection in developing of autoimmune response. 2. Material and methods2.1. Autoantigens analysis. Amino acid sequences of autoantigens for systemic lupus erythematosus were retrieve from autoantigen … " - Human autoantigen database

Human autoantigen database

Autoantibodies (AAb) are antibodies that bind to individual's own antigens. Their production can be affected by genetic predisposition, environment, viruses and pathogens (via epitope mimicking) and chemicals, etc. In the last three decades numerous studies have been devoted to elucidating the … See more Our data collection relied on the text mining of AAg-related PubMed abstracts. Bio-entity recognition and extraction from these abstracts for human AAg candidates were performed by our custom developed ontology-based bio … See more Since the first AAg paper appeared in 1945, more than 120 000 papers have been published and 1000 AAgs have been identified. Some of … See more We provide a user-friendly web interface that facilitates searching, exploring information and updating the AAgAtlas 1.0 database (http://biokb.ncpsb.org/aagatlas/) (Figure 4). The … See more AAgAtlas database runs entirely on open software (MySQL database server, Apache web server with the interface written in PHP, … See more Web19 Oct 2016 · Interestingly, our unbiased screen revealed autoantibody specificities against several known autoantigens present in AAgAtlas 1.0, a human autoantigen database, …

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Web1 Jan 2024 · Autoantibodies are antibodies against host self-proteins (autoantigens), which play significant roles in homeostasis maintenance and diseases with autoimmune disorders. Numerous papers were published in the past decade on the identification of human autoantigens in different human diseases. Web19 Oct 2016 · Europe PMC is an archive of life sciences journal literature. Search life-sciences literature (Over 39 million (Over 39 million

Web(AAgAtlas database 1.0). The database provides a user-friendly interface to conveniently browse, re-trieve and download human autoantigens as well as their associated … WebFrom the ‘Home’ page, the users can see the introduction of AAgAtlas 1.0 database and search for the gene or disease of their interest. From the ‘Browse & Download’, the users …

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WebSupplementary Table 2 provides summary statistics about these reactive proteins, including whether they are previously defined autoantigens according to the human autoantigen database AAgAtlas 1.0 ...

Web4 Jan 2024 · The database provides a user-friendly interface to conveniently browse, retrieve and download human autoantigens as well as their associated diseases. The … romantic hindi songs 2020WebAAgAtlas 1.0 provides a user-friendly interface to conveniently browse, retrieve, and download human autoantigen genes, their functional annotation, related diseases, and … romantic hindi serialsWeb1 Sep 2002 · Valenta et al. published a DNA sequence for an expressed human autoantigen named HOMS-1 (GenBank accession no. Y14314) with almost complete sequence identity to SART-1; this sequence is unlikely to represent the full-length cDNA, since it leaves out the first 38 amino acids compared with the Itoh et al. sequence. romantic hindi serials listWebAutoantibodies are antibodies against host self-proteins (autoantigens), which play significant roles in homeostasis maintenance and diseases with autoimmune disorders. … romantic hindi songs latestWeb19 Oct 2016 · The database is freely accessible at http://biokb.ncpsb.org/aagatlas/ We believe this database will be a valuable resource to track and understand human autoantigens as well as to investigate their functions in basic and translational research. Free full text Nucleic Acids Res. 2024 Jan 4; 45(Database issue): D769–D776. romantic hindi songs 2021WebMany autoantigens consist of RNA-binding proteins complexed with RNA molecules. These ribonucleoproteins are highly conserved, and many have microbial orthologs. There is increasing evidence that the microbiome plays an important role in the development of many autoimmune diseases. romantic hindi songs albumWebNational Center for Biotechnology Information romantic hindi songs on youtube